Interrelationships between the kinetics of VLDL subspecies and HDL catabolism in abdominal obesity: a multicenter tracer kinetic study.
Identifieur interne : 003780 ( Main/Exploration ); précédent : 003779; suivant : 003781Interrelationships between the kinetics of VLDL subspecies and HDL catabolism in abdominal obesity: a multicenter tracer kinetic study.
Auteurs : Bruno Vergès [Finlande] ; Martin Adiels ; Jan Boren ; Peter Hugh Barrett ; Gerald F. Watts ; Dick Chan ; Laurence Duvillard ; Sanni Söderlund ; Niina Matikainen ; Juhani Kahri ; Isabelle Robin ; Marja-Riitta TaskinenSource :
- The Journal of clinical endocrinology and metabolism [ 1945-7197 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- métabolisme : Apolipoprotéines, Foie, Lipoprotéines HDL, Lipoprotéines VLDL, Obésité abdominale, Tissu adipeux.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mâle, Sujet âgé.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Apolipoproteins, Lipoproteins, HDL, Lipoproteins, VLDL.
- metabolism : Adipose Tissue, Liver, Obesity, Abdominal.
- Adult, Aged, Female, Humans, Male, Middle Aged.
Abstract
Low plasma high-density lipoprotein (HDL) cholesterol is a major abnormality in abdominal obesity. This relates due to accelerated HDL catabolism, but the underlying mechanism requires further elucidation. The relationships between HDL catabolism and other variables that may be modified in abdominal obesity, such as very low-density lipoprotein (VLDL) subspecies (VLDL1, VLDL2) kinetics, liver fat, or visceral adiposity, remain to be investigated.
DOI: 10.1210/jc.2014-2365
PubMed: 25077901
Affiliations:
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Le document en format XML
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Departments of Molecular and Clinical Medicine (M.A., J.B.) and Mathematical Sciences (M.A.), University of Gothenburg, S-405 30 Gothenburg, Sweden; Faculty of Engineering, Computing, and Mathematics (H.B.), University of Western Australia, Perth, Western Australia 6872, Australia; Lipid Disorders Clinic (H.B., G.F.W., D.C.), Metabolic Research Centre, Department of Cardiovascular Medicine, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia 6847, Australia; and Heart and Lung Centre (S.S., N.M., M.-R.T.), Helsinki University Central Hospital and Research Programs' Unit, Department of Diabetes and Obesity, University of Helsinki, and Department of Medicine (N.M., J.K.), Helsinki University Central Hospital, 00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Departments of Endocrinology-Diabetology (B.V., I.R.) and Medical Biology (L.D.), University Hospital, and INSERM CRI 866 (B.V., L.D.), 21000 Dijon, France; Departments of Molecular and Clinical Medicine (M.A., J.B.) and Mathematical Sciences (M.A.), University of Gothenburg, S-405 30 Gothenburg, Sweden; Faculty of Engineering, Computing, and Mathematics (H.B.), University of Western Australia, Perth, Western Australia 6872, Australia; Lipid Disorders Clinic (H.B., G.F.W., D.C.), Metabolic Research Centre, Department of Cardiovascular Medicine, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia 6847, Australia; and Heart and Lung Centre (S.S., N.M., M.-R.T.), Helsinki University Central Hospital and Research Programs' Unit, Department of Diabetes and Obesity, University of Helsinki, and Department of Medicine (N.M., J.K.), Helsinki University Central Hospital, 00290 Helsinki</wicri:regionArea><wicri:noRegion>00290 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Adiels, Martin" sort="Adiels, Martin" uniqKey="Adiels M" first="Martin" last="Adiels">Martin Adiels</name></author><author><name sortKey="Boren, Jan" sort="Boren, Jan" uniqKey="Boren J" first="Jan" last="Boren">Jan Boren</name></author><author><name sortKey="Barrett, Peter Hugh" sort="Barrett, Peter Hugh" uniqKey="Barrett P" first="Peter Hugh" last="Barrett">Peter Hugh Barrett</name></author><author><name sortKey="Watts, Gerald F" sort="Watts, Gerald F" uniqKey="Watts G" first="Gerald F" last="Watts">Gerald F. Watts</name></author><author><name sortKey="Chan, Dick" sort="Chan, Dick" uniqKey="Chan D" first="Dick" last="Chan">Dick Chan</name></author><author><name sortKey="Duvillard, Laurence" sort="Duvillard, Laurence" uniqKey="Duvillard L" first="Laurence" last="Duvillard">Laurence Duvillard</name></author><author><name sortKey="Soderlund, Sanni" sort="Soderlund, Sanni" uniqKey="Soderlund S" first="Sanni" last="Söderlund">Sanni Söderlund</name></author><author><name sortKey="Matikainen, Niina" sort="Matikainen, Niina" uniqKey="Matikainen N" first="Niina" last="Matikainen">Niina Matikainen</name></author><author><name sortKey="Kahri, Juhani" sort="Kahri, Juhani" uniqKey="Kahri J" first="Juhani" last="Kahri">Juhani Kahri</name></author><author><name sortKey="Robin, Isabelle" sort="Robin, Isabelle" uniqKey="Robin I" first="Isabelle" last="Robin">Isabelle Robin</name></author><author><name sortKey="Taskinen, Marja Riitta" sort="Taskinen, Marja Riitta" uniqKey="Taskinen M" first="Marja-Riitta" last="Taskinen">Marja-Riitta Taskinen</name></author></analytic><series><title level="j">The Journal of clinical endocrinology and metabolism</title><idno type="eISSN">1945-7197</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adipose Tissue (metabolism)</term><term>Adult</term><term>Aged</term><term>Apolipoproteins (metabolism)</term><term>Female</term><term>Humans</term><term>Lipoproteins, HDL (metabolism)</term><term>Lipoproteins, VLDL (metabolism)</term><term>Liver (metabolism)</term><term>Male</term><term>Middle Aged</term><term>Obesity, Abdominal (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Apolipoprotéines (métabolisme)</term><term>Femelle</term><term>Foie (métabolisme)</term><term>Humains</term><term>Lipoprotéines HDL (métabolisme)</term><term>Lipoprotéines VLDL (métabolisme)</term><term>Mâle</term><term>Obésité abdominale (métabolisme)</term><term>Sujet âgé</term><term>Tissu adipeux (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Apolipoproteins</term><term>Lipoproteins, HDL</term><term>Lipoproteins, VLDL</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Adipose Tissue</term><term>Liver</term><term>Obesity, Abdominal</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Apolipoprotéines</term><term>Foie</term><term>Lipoprotéines HDL</term><term>Lipoprotéines VLDL</term><term>Obésité abdominale</term><term>Tissu adipeux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Sujet âgé</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Low plasma high-density lipoprotein (HDL) cholesterol is a major abnormality in abdominal obesity. This relates due to accelerated HDL catabolism, but the underlying mechanism requires further elucidation. The relationships between HDL catabolism and other variables that may be modified in abdominal obesity, such as very low-density lipoprotein (VLDL) subspecies (VLDL1, VLDL2) kinetics, liver fat, or visceral adiposity, remain to be investigated.</div></front></TEI><affiliations><list><country><li>Finlande</li></country></list><tree><noCountry><name sortKey="Adiels, Martin" sort="Adiels, Martin" uniqKey="Adiels M" first="Martin" last="Adiels">Martin Adiels</name><name sortKey="Barrett, Peter Hugh" sort="Barrett, Peter Hugh" uniqKey="Barrett P" first="Peter Hugh" last="Barrett">Peter Hugh Barrett</name><name sortKey="Boren, Jan" sort="Boren, Jan" uniqKey="Boren J" first="Jan" last="Boren">Jan Boren</name><name sortKey="Chan, Dick" sort="Chan, Dick" uniqKey="Chan D" first="Dick" last="Chan">Dick Chan</name><name sortKey="Duvillard, Laurence" sort="Duvillard, Laurence" uniqKey="Duvillard L" first="Laurence" last="Duvillard">Laurence Duvillard</name><name sortKey="Kahri, Juhani" sort="Kahri, Juhani" uniqKey="Kahri J" first="Juhani" last="Kahri">Juhani Kahri</name><name sortKey="Matikainen, Niina" sort="Matikainen, Niina" uniqKey="Matikainen N" first="Niina" last="Matikainen">Niina Matikainen</name><name sortKey="Robin, Isabelle" sort="Robin, Isabelle" uniqKey="Robin I" first="Isabelle" last="Robin">Isabelle Robin</name><name sortKey="Soderlund, Sanni" sort="Soderlund, Sanni" uniqKey="Soderlund S" first="Sanni" last="Söderlund">Sanni Söderlund</name><name sortKey="Taskinen, Marja Riitta" sort="Taskinen, Marja Riitta" uniqKey="Taskinen M" first="Marja-Riitta" last="Taskinen">Marja-Riitta Taskinen</name><name sortKey="Watts, Gerald F" sort="Watts, Gerald F" uniqKey="Watts G" first="Gerald F" last="Watts">Gerald F. Watts</name></noCountry><country name="Finlande"><noRegion><name sortKey="Verges, Bruno" sort="Verges, Bruno" uniqKey="Verges B" first="Bruno" last="Vergès">Bruno Vergès</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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